Transition from Interictal to Ictal Activity in Limbic NetworksIn Vitro
نویسندگان
چکیده
منابع مشابه
Transition from interictal to ictal activity in limbic networks in vitro.
The transition from brief bursts of synchronous population activity characteristic of interictal epileptiform discharges (IEDs) to more prolonged epochs of population activity characteristic of seizures (ictal-like activity) was recorded in juvenile rat hippocampal-entorhinal cortex slices and hippocampal slices using multiple-site extracellular electrodes. Epileptiform activity was elicited by...
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In human partial epilepsies, as well as in experimental models of chronic and/or acute epilepsy, the role of inhibition and the relationship between the inhibition and excitation and epileptogenesis has long been questioned. Besides experimental methods carried out either in vitro (human or animal tissue) or in vivo (animals), pathophysiological mechanisms can be approached by direct recording ...
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It is widely assumed that the recording of EEG infraslow activity (ISA) requires direct current amplifiers. Yet, it has been shown during the past decade that conventional EEG systems can record activity between 0.01 and 0.1 Hz and that this frequency band contains additional information, especially in regard to seizure onset. To delineate the characteristics of background ISA, 24-hour scalp an...
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1 INSERM U739, Faculté de Médecine Pitié-Salpêtrière, Paris, France 2 Institute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary 3 National Institute of Neurosurgery, Budapest, Hungary 4 Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary 5 Epilepsy Unit, Hôpital Pitié-Salpêtrière, Paris, France 6 Neurosurgery Unit, Hôpital Pitié-Salpêtrière, Par...
متن کاملNeuronal network model of interictal and recurrent ictal activity.
We propose a neuronal network model which undergoes a saddle node on an invariant circle bifurcation as the mechanism of the transition from the interictal to the ictal (seizure) state. In the vicinity of this transition, the model captures important dynamical features of both interictal and ictal states. We study the nature of interictal spikes and early warnings of the transition predicted by...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2003
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.23-21-07873.2003